The Reformed Church of Loysburg was formally organized in 1848. These German immigrants had been meeting in homes and in a privately-owned school building for worship and Sunday school in the preceding years. Worship services were conducted in both German and English.

    The first building was consecrated in June, 1849. It was built of brick on a lot donated by Major James Patton, a prominent local property holder at the time. Maj. Patton had the name Loysburg changed to Pattonsville. The $1,700 cost of the structure was met by subscription on the founders and others in the community. Members donated much of the material and labor. It was 50 by 25 feet. The pastor was Rev. Matthew Irvine, who served the Bloody Run (Everett) Charge, consisting of several churches. In 1850 the Yellow Creek and Pattonsville (Loysburg) congregations were transferred to the Martinsburg Charge and Rev. Frederick A. Rupley became the pastor.

     In July of 1853 the church leaders called Rev. Samuel Philips of Ohio as pastor. The congregation adopted a charter prepared by him and took the name of “German Reformed Church at Pattonsville.” The name “St. John’s” was first used in 1856. The Yellow Creek (St. Paul’s) and Pattonsville congregations became a two-church charge in 1855.In 1884 the residents of Pattonsville successfully petitioned the Post Office Department to change the community’s name back to its original Loysburg.

     No record shows when a parsonage was built, but an 1877 map shows the parsonage and church at their present locations.

    In 1881 the congregation decided a larger building was needed and the present brick building was completed on the same site. The new building was 55 by 36 feet and cost about $3,500. Many improvements have been made since, particularly the excavation of the basement to create a kitchen, rest rooms and fellowship hall.Also, the creation of an adjacent parking lot, the remodeling of the sanctuary and the addition of an electronic organ were all completed in the 1950s. A two-story Sunday School wing was built in 1986-87, and the organ was replaced the following year.

    In 1898 the Loysburg congregation was instrumental in establishing a sister church at Lafayetteville. However, after its building was damaged by wind in 1927, its members united with the Loysburg congregation.

    In 1933 the Loysburg congregation was separated from the Yellow Creek Charge and made part of the Hickory Bottom Charge. This remained a three-point charge with the Mount Pleasant and East Sharpsburg congregations until Mount Pleasant separated from the charge in 2004 and East Sharpsburg in early 2006, leaving St. John’s of Loysburg as a stand-alone congregation.

    Through merger, the German Reformed synods became part of the Evangelical and Reformed denomination in 1934 and part of the United Church of Christ in 1956. In 2005 the congregation voted to withdraw from the United Church of Christ and apply for membership with the Conservative Congregational Christian Conference. The congregation reverted to its earlier name, St. John’s Reformed Church of Loysburg.

    The Conservative Congregational Christian Conference (CCCC) was officially formed in 1948 and welcomes all congregations that believe strongly in the autonomy of each local church under the headship of Christ. Member churches include those who are Congregational, Christian, Evangelical and Reformed in their background, as well as independent community churches.